Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

The findings of a new study suggest that a ketogenic diet — which is low in carbohydrates and protein, but high in fat — helps to kill pancreatic cancer cells when combined with a triple-drug therapy. In laboratory experiments, the ketogenic diet decreased glucose (sugar) levels in the tumor, suggesting the diet helped starve the cancer. In addition, this diet elevated ketone bodies produced by the liver, which put additional stress on the cancer cells.

Scientists have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors.

The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study.

A new computational approach successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.

A new form of magnetic resonance imaging (MRI) that makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.

New research finds that patients with ASXL1-mutant chronic myelomonocytic leukemia — an uncommon type of cancer of the bone marrow — have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster. The ASXL1 genetic mutation also can transform the disease into the more aggressive acute myeloid leukemia.

Researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.

Metastases in cancer are often caused by a few abnormal cells. These behave more aggressively than the other cancer cells in a tumor. Researchers are now on a method to detect these cells.

Researchers have genetically engineered a microbial encapsulation system for therapeutic bacteria that can hide them from immune systems, enabling them to reach tumors more effectively and kill cancer cells in mice.

New research has linked phthalates, commonly called the ‚everywhere chemical,‘ to higher incidence of specific childhood cancers.

A research team has discovered novel metabolic mechanisms that contribute to how ovarian cancer escapes from immune attack, and how combination therapies can exploit these pathways to improve ovarian cancer treatment.

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a new study.

Scientists have developed a genetic screening platform to identify genes that can enhance immune cells to make them more persistent and increase their ability to eradicate tumor cells.

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study suggests.

Treating cancer and other diseases with laser light is not currently considered routine, but new approaches using nanoparticles show some promise in improving existing techniques. Researchers review the status of the field and by combining photothermal therapy or photodynamic therapy with nanomaterials, they have been able to apply these types of phototherapies while also delivering drugs to sites in the body that are otherwise inaccessible. It is also possible to combine PTT and PDT into a single treatment, creating an even more powerful treatment method.

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers have now found an unusual way of stabilizing the protein and making it more potent. By adding a spider silk protein to p53, they show that it is possible to create a protein that is more stable and capable of killing cancer cells.

Irradiation with fast protons is a more effective and less invasive cancer treatment than X-rays. However, modern proton therapy requires large particle accelerators, which has experts investigating alternative accelerator concepts, such as laser systems to accelerate protons. Such systems are deployed in preclinical studies to pave the way for optimal radiation therapy. A research team has now successfully tested irradiation with laser protons on animals.

New research has begun to unravel the mystery of why a particular form of leukaemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children. Scientists have now found subtle differences in the cell type that causes B acute lymphoblastic leukaemia (B-ALL) that may help to explain why some cases are more severe than others.

Both nanomedicines and metronomic scheduling — when medications are given at lower, more frequent doses — can correct abnormalities surrounding tumors that help protect cancer cells and foster their growth and spread. Combining nanomedicines and metronomic scheduling may help improve cancer treatment strategies.

Scientists have identified a way to ’supercharge‘ tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat.

New research has identified that the frequently used chemotherapy drug (5-FU or Fluorouracil) is 100 per cent more effective at targeting tumors (rather than surrounding tissues) when administered using an optimized liposomal formulation.

With the resurgence of interest in cancer metabolism, researchers are coming to realize that there is more to a cell’s biochemistry than once thought.

Scientists may better understand and test for the genetic variations that cause cancer and other heritable diseases through the application of federated analysis, a novel strategy for securely sharing and analyzing genomic data developed at the UC Santa Cruz Genomics Institute.

Researchers have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations in the RAS gene, which are famously difficult to treat and account for about one in four cancer deaths.