Schlagwort: cancer
Blood type may offer insights into risk of blood clot in people with cancer
14. April 2022
A new study suggests that people with cancer and non-O blood types, such as types A, B, and AB, face an increased risk of developing venous thromboembolism (VTE), or blood clots in the veins, three months after their initial diagnosis. Scientists have long strived to understand the risk factors for VTE, the leading cause of preventable hospital deaths in the United States. Existing assessments use factors like tumor or cancer type to detect those at high risk of VTE. Yet, many patients without these diagnoses still develop life-threatening blood clots but go unidentified.
Epigenetic regulator explains why some lung cancer patients become resistant to common therapeutics
13. April 2022
Cellular biologists discover why some patients become resistant to standard treatments for nonsmall cell lung cancer.
New platform optimizes selection of combination cancer therapies
13. April 2022
Researchers have developed a new computational tool to select optimal combination therapies for patients with cancer based on the co-occurring alterations in a given tumor.
Omicron: Number of vaccine breakthroughs in cancer patients on the rise, study finds
13. April 2022
For cancer patients, COVID-19 poses a particular risk due to their often compromised immune systems. Now, a study shows that, due to Omicron, there is an increasing number of breakthrough infections in people with cancer, especially while they are undergoing cancer therapy.
Study suggests why most smokers don’t get lung cancer
12. April 2022
Cigarette smoking is overwhelmingly the main cause of lung cancer, yet only a minority of smokers develop the disease. A study suggests that some smokers may have robust mechanisms that protect them from lung cancer by limiting mutations. The findings could help identify those smokers who face an increased risk for the disease and therefore warrant especially close monitoring.
Friend or foe? The immune system collaborates with blood cancer cells
12. April 2022
An international study demonstrates that the body’s immune system attacks itself in a rare type of blood cancer. Consequently, treatment should be targeted at the immune system as well, not only the cancer cells.
Evidence in mice that bacteria in tumors help cancer cells metastasize
8. April 2022
Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report.
Exercise shown to release protein reducing bowel cancer risk
8. April 2022
Experts have identified for the first time exactly how exercise can lower your risk of getting bowel cancer and slow the growth of tumors.
Researchers look to licorice for promising cancer treatments
7. April 2022
A research review into molecular insights of a licorice-derived substance called glycyrrhizin for preventing or treating cancer suggests further research could lead to specific agents for clinical use.
Gene deletion behind anomaly in blood cancer cells
6. April 2022
Although clinical labs have known for almost a century that a oddly shaped nucleus resembling pince-nez glasses in blood cells could indicate leukemia, the cause of this anomaly remained unknown. Scientists have now discovered that loss of nuclear Lamin B1 induces defects in the nuclear morphology and in human hematopoietic [blood-forming] stem cells associated with malignancy. The scientists went on to detail that lamin B1 deficiency alters genome organization. This in turn causes expansion of blood-forming stem cells, a bias towards their becoming myeloids, genome instability due to defective DNA damage repair and other problems that set the stage for cancer.
Gene deletion behind anomaly in blood cancer cells
6. April 2022
Although clinical labs have known for almost a century that a oddly shaped nucleus resembling pince-nez glasses in blood cells could indicate leukemia, the cause of this anomaly remained unknown. Scientists have now discovered that loss of nuclear Lamin B1 induces defects in the nuclear morphology and in human hematopoietic [blood-forming] stem cells associated with malignancy. The scientists went on to detail that lamin B1 deficiency alters genome organization. This in turn causes expansion of blood-forming stem cells, a bias towards their becoming myeloids, genome instability due to defective DNA damage repair and other problems that set the stage for cancer.
Cause of metastasis in prostate cancer discovered
6. April 2022
Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer.
Cause of metastasis in prostate cancer discovered
6. April 2022
Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer.
The nanodrug that attacks cancer twice
6. April 2022
A single nanoparticle does two jobs: enhancing the effectiveness of chemotherapy and reinvigorating the immune system.
Immune system ‘sentinel’ cells key to maintaining and regulating response to immunotherapy
2. April 2022
The presence of dendritic cells, so-called ‘sentinel’ immune cells, is vital to maintain and regulate the balance of the body’s immune response. Researchers have discovered an essential role of these cells in the treatment of cancer and severe viral infections.
Cancer repair mechanism could be potential drug target
1. April 2022
Searching for ways to extend the survival benefit of targeted therapies, a team led by researchers has identified a potential new tactic to disrupt the repair mechanism that cancer cells use after treatment, blunting their ability to regenerate. The approach could present a new treatment strategy.
Living donation opens new doors for colorectal cancer patients in need of liver transplants
31. März 2022
A study is the first in North America to demonstrate that living-donor liver transplant is a viable option for patients who have systemically controlled colorectal cancer and liver tumors that cannot be surgically removed.
Living donation opens new doors for colorectal cancer patients in need of liver transplants
31. März 2022
A study is the first in North America to demonstrate that living-donor liver transplant is a viable option for patients who have systemically controlled colorectal cancer and liver tumors that cannot be surgically removed.
Hands, feet, and fins: The connection that explains acral melanoma
31. März 2022
Scientists are using zebrafish to understand human skin cancer that attacks the hands and feet.
Hands, feet, and fins: The connection that explains acral melanoma
31. März 2022
Scientists are using zebrafish to understand human skin cancer that attacks the hands and feet.
New algorithm will improve bowel-cancer patient care
31. März 2022
An algorithm which can predict how long a patient might spend in hospital if they’re diagnosed with bowel cancer could save the money and help patients feel better prepared.
Study finds 10-second videos predict blood cancer relapse
30. März 2022
Ten-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
Distinct classes of fibroblasts in tumors play opposing roles, promoting or restraining pancreatic cancer growth
30. März 2022
Researchers discovered that two distinct classes of fibroblast cells accumulate in pancreatic tumors and play opposing roles to promote and restrain pancreatic cancer growth. Appropriately targeting these cells may offer options to improve treatment outcomes.
Black patients with cancer fare worse with COVID-19, study shows
29. März 2022
Lack of access to health care, social determinants of health, preexisting comorbidities and reduced access to clinical research are common to both cancer and COVID-19 in Black individuals. Together these two diseases create a perfect storm in this population, a new study indicates.
Researchers offer new treatment protocol for advanced head and neck cancer
29. März 2022
The current treatment of patients diagnosed with advanced or metastatic head and neck cancer (HNC) is ineffective. Researchers have investigated and validated a potential treatment combination against the aggressive disease driven by hyper-activation of a specific signaling pathway, which is found in over 40 percent of HNC patients.