Early settlement dynamics in the Pacific revealed through ancient DNA

Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tübingen team examines human migrations from the past 3,000 years that shaped diversity of Remote Oceania Quelle: IDW Informationsdienst Wissenschaft

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Alte DNA lässt Dynamik der frühen Besiedlung pazifischer Inseln erkennen

Team des Senckenberg Centre for Human Evolution and Palaeoenvironment an der Universität Tübingen untersucht Wanderungen der Menschen der vergangenen 3.000 Jahre im Südpazifik Quelle: IDW Informationsdienst Wissenschaft

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New Single-Cell Atlas Reveals the Plasticity of the Human Pancreas

An EU-funded research project coordinated by the Berlin Institute of Health at Charité (BIH) has uncovered how the pancreas develops, adapts, and changes in disease. The study has now been published in Cell Metabolism. Quelle: IDW Informationsdienst Wissenschaft

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Resistance Training Activates the Muscle Repair Machinery

Researchers from the Universities of Hildesheim, Bonn, and Freiburg have now uncovered how human skeletal muscle responds to resistance exercise at the molecular level. Their findings provide new insights that could help optimize training programs for athletes, improve rehabilitation strategies, and counteract age-related muscle loss. Resistance training is essential for maintaining healthy skeletal muscle throughout life. The World Health Organization now recommends moderate muscle-strengthening activities at least twice a week, even for older adults, to help prevent the loss of muscle strength. The new study is published in the latest issue of Nature Communications. Quelle: IDW Informationsdienst Wissenschaft

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Größeres Gehirn, kleineres Gesicht: Menschliche Evolution verlief anders als gedacht

Eine heute in „Nature Communications“ veröffentlichte Studie legt nahe, dass zwei der bekanntesten Trends der menschlichen Evolution – das Wachstum des Gehirns sowie die Verkleinerung von Gesicht und Kiefer – möglicherweise weit weniger auf gezielte natürliche Selektion zurückgehen, als Wissenschaftler*innen lange angenommen haben. Die Ergebnisse von Forschenden der University of Tennessee – Knoxville und des Senckenberg Centre for Human Evolution and Palaeoenvironment (SHEP) an der Universität Tübingen deuten stattdessen auf einen langsameren und vermutlich stärker eingeschränkten Evolutionsprozess hin, als es die traditionelle Lehrbuchdarstellung nahelegt. Quelle: IDW Informationsdienst Wissenschaft

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When Old Data Gains New Relevance: Historical Study on Brain Convolutions Confirmed After 150 Years

Renate Schweizer and her team receive the Replication Prize from the Organization for Human Brain Mapping Quelle: IDW Informationsdienst Wissenschaft

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Environmental DNA Reveals Impact of Climate and Humans on Global River Fish Biodiversity

A global analysis of fish biodiversity using environmental DNA (eDNA) reveals how human activity and climate influence biodiversity patterns in river ecosystems. An international research team led by the University of Zurich, Eawag and Yunnan University has found that in warmer climates biodiversity accumulation is more pronounced as river catchment size increases, while human activities weaken this relationship. Quelle: IDW Informationsdienst Wissenschaft

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Slow Breathing Can Influence Brain Activity and Decision Behavior

A new study from the German Institute of Human Nutrition Potsdam–Rehbruecke (DIfE) and Charité – Universitätsmedizin Berlin shows for the first time that targeted control of human breathing rhythm can influence decision behavior by modulating heart and brain function. The research team led by Prof. Soyoung Q Park was able to demonstrate that prolonged exhalation increases heartrate variability and brain’s reward sensitivity, thus enabling us to make bolder decisions. The study was published in the journal Neuron. Quelle: IDW Informationsdienst Wissenschaft

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Goosebump Moments in Archaeological Research

How did people live centuries ago? How did they see themselves? How were they perceived by others? Today, archaeology uses modern methods to examine skeletons, personal belongings, burial practices, material culture and social and spatial relationships. The book “Human Identities in the Archaeological Record: Interdisciplinary Perspectives from Late Antiquity to the Modern Period” shows how past identities can be reconstructed from this evidence. Quelle: IDW Informationsdienst Wissenschaft

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Hiding in the central nervous system: using cerebral organoids to better understand Ebola virus biology

Hamburg and New York, 12 June 2026 – Following infection, Ebola virus can survive unnoticed in the human body for months or even years, hiding in areas with little immune surveillance like the central nervous system. The danger is that those affected may have an Ebola virus disease relapse or even trigger a new outbreak. Using a cerebral organoid model, researchers at the Bernhard Nocht Institute for Tropical Medicine (BNITM) and the Icahn School of Medicine at Mount Sinai (ISMMS), together with other collaborators, gained valuable insights into the mechanisms of such Ebola virus persistence. The findings were recently published…

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Gänsehautmomente in der archäologischen Forschung

Wie lebten Menschen vor Jahrhunderten? Wie sahen sie sich selbst? Wie wurden sie von anderen wahrgenommen? Die Archäologie untersucht heute mit modernen Methoden Skelette, Besitz, Bestattungsbräuche sowie soziale und räumliche Beziehungen. Wie sich daraus die Identität von Menschen aus der Vergangenheit rekonstruieren lässt, zeigt das Buch „Human Identities in the Archaeological Record: Interdisciplinary Perspectives from Late Antiquity to the Modern Period“. Quelle: IDW Informationsdienst Wissenschaft

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Ageing in the selection shadow

A review article published in “Nature Reviews Genetics” brings together evolutionary theory, comparative genomics and large-scale human genetics to explain why we age and why ageing rates differ among individuals and species. The two authors—from the Leibniz Institute on Aging (FLI) in Jena and University College London in London—describe how, because modern humans now routinely survive into old age, we live with the late-life consequences of biological pathways that natural selection optimized for youth, and of harmful mutations that act too late in life for selection to clear them efficiently. It points to shared genetic causes and conserved therapeutic targets….

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Human traits beyond inherited genes: ISTA scientists reveal genetic connections between generations

Our parents’ genes, even the ones we didn’t inherit, leave a measurable lasting imprint on our lives. An international team led by researchers at the Institute of Science and Technology Austria (ISTA) and the Norwegian Institute of Public Health developed a new approach to analyze genetic data from tens of thousands of families. The study, published this Tuesday in Cell Genomics, found that for height, body weight, and school test performance, the environment shaped by our parents’ genes can be nearly as important as the genes we actually inherited from them. Quelle: IDW Informationsdienst Wissenschaft

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2th EHS-Symposium: Environmental health risks in a changing world

Human health risks associated with the natural environment and the human activities therein are interconnected, comprise a wide range of spatial scales and are temporally dynamic and changing. It has been recognized that the health of our natural environment and human health are inextricably linked. Our planet is changing in an unprecedented rate and new challenges emerge from climate and environmental change, globalization, urbanization, and lifestyle changes. Quelle: IDW Informationsdienst Wissenschaft

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Understanding Virus Signals

It is only recently that scientists have been able to observe tiny viruses and their behavior. Bacteria are a thousand times larger than viruses, and our human cells are a thousand times larger than bacteria. We still don’t know what viruses are and how they can have such a complex lifestyle while consisting of just […] Quelle: John Lieff, M.D

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A global assessment of cancer genomic alterations in epigenetic mechanisms

Muhammad A Shah, Emily L Denton, Cheryl H Arrowsmith, Mathieu Lupien and Matthieu Schapira Abstract Background The notion that epigenetic mechanisms may be central to cancer initiation and progression is supported by recent next-generation sequencing efforts revealing that genes involved in chromatin-mediated signaling are recurrently mutated in cancer patients. Results Here, we analyze mutational and transcriptional profiles from TCGA and the ICGC across a collection 441 chromatin factors and histones. Chromatin factors essential for rapid replication are frequently overexpressed, and those that maintain genome stability frequently mutated. We identify novel mutation hotspots such as K36M in histone H3.1, and uncover…

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Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

Daniel Smeets, Yolanda Markaki, Volker J Schmid, Felix Kraus, Anna Tattermusch, Andrea Cerase, Michael Sterr, Susanne Fiedler, Justin Demmerle, Jens Popken, Heinrich Leonhardt, Neil Brockdorff, Thomas Cremer1, Lothar Schermelleh and Marion Cremer Abstract Background A Xist RNA decorated Barr body is the structural hallmark of the compacted inactive X territory in female mammals. Using super-resolution three-dimensional structured illumination microscopy (3D-SIM) and quantitative image analysis, we compared its ultrastructure with active chromosome territories (CTs) in human and mouse somatic cells, and explored the spatio-temporal process of Barr body formation at onset of inactivation in early differentiating mouse embryonic stem cells (ESCs)….

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The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats

Susanne Rittinghausen, Anja Hackbarth, Otto Creutzenberg, Heinrich Ernst, Uwe Heinrich, Albrecht Leonhardt and Dirk Schaudien Abstract Background Biological effects of tailor-made multi-walled carbon nanotubes (MWCNTs) without functionalization were investigated in vivo in a two-year carcinogenicity study. In the past, intraperitoneal carcinogenicity studies in rats using biopersistent granular dusts had always been negative, whereas a number of such studies with different asbestos fibers had shown tumor induction. The aim of this study was to identify possible carcinogenic effects of MWCNTs. We compared induced tumors with asbestos-induced mesotheliomas and evaluated their relevance for humans by immunohistochemical methods. Methods A total of 500…

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