New technique may lead to safer stem cell transplants
12. November 2021
Studying mice, researchers have developed a method of stem cell transplantation that does not require radiation or chemotherapy. Instead, the strategy takes an immunotherapeutic approach, combining the targeted elimination of blood-forming stem cells in the bone marrow with immune-modulating drugs to prevent the immune system from rejecting the new donor stem cells.
CRISPR screen identifies new anti-inflammatory drug target
12. November 2021
A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, researchers have discovered. They report that inhibiting or genetically deleting the enzyme, called MTHFD2, reduced disease severity in multiple inflammatory disease models.
Corona-Update: Österreich ab Sonntag wieder Hochrisikogebiet
12. November 2021
Nicht Geimpfte und nicht Genesene müssen bei der Einreise von Österreich nach Deutschland bald in Quarantäne. Hierzulande grassiert das Virus in Sachsen am stärksten, auch in Thüringen und Bayern ist die Lage dramatisch. Der Überblick.
How alike are the cancer cells from a single patient?
12. November 2021
Using an experimental system involving new genetic technology, researchers analyzed the gene expression signatures of a representative sample of barcoded leukemia cells. After implanting some of the leukemia cells in mice, they discovered that distinct gene expression signatures correlated with the various organs where the cancer cells ended up. They were also able to identify previously unknown genes that are involved in disease progression and chemotherapy resistance, which may offer new targets for treatment.
Matthias Maurer im Weltall: Gruseln tut’s mir in keinem Moment
12. November 2021
100 Experimente und ein Außeneinsatz: volles Programm für Matthias Maurer. Nach mehrfach verschobenem Start hob der deutsche Astronaut in der vergangenen Nacht endlich in Richtung ISS ab. Dort soll er bis April bleiben.
Corona-News: Markus Söder sagt Staatsbankett mit Königin Margrethe ab
11. November 2021
Die AfD-Fraktionschefin Weidel hat das Coronavirus, grippeähnliche Symptome inklusive. Der Bundestag beschließt 3G fürs Plenum – gegen AfD-Stimmen. Und: Karnevalssession in Köln unter 2G-Regeln eingeläutet. Der Überblick.
Die vielen Formen und Grade des Schutzes
11. November 2021

Wer braucht wann eine Auffrischung der Covid-Impfung? Eine Studie hat nun die Wirkung der RNA-Impfstoffe verglichen und kommt zu guten Ergebnissen.
How gene mutation boosts cancer risk
11. November 2021
Scientists have revealed why a mutation in the UTX gene disrupts cells‘ ability to suppress tumors.
Data available for training AI to spot skin cancer are insufficient and lacking in pictures of darker skin
11. November 2021
The images and accompanying data available for training artificial intelligence (AI) to spot skin cancer are insufficient and include very few images of darker skin, according to new research.
Landmark study points to source of rapid aging, chronic inflammation in people living with HIV
10. November 2021
In a groundbreaking study of people living with HIV, researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.
Corona: Leopoldina-Forscher fordern Impfpflicht für bestimmte Berufe
10. November 2021
Zu wenig unternimmt die Politik gegen die vierte Welle, so die Diagnose der Forscher. Sie fordern: Arbeitnehmer müssten ihren Status transparent machen – und für Pfleger oder Lehrer sollte die Impfung vorgeschrieben werden.
Drug used to prevent miscarriage increases risk of cancer in offspring
10. November 2021
Exposure in utero to a drug used to prevent miscarriage can lead to an increased risk of developing cancer, according to researchers.
Safety concerns raised for neuroblastoma candidate drug
10. November 2021
Scientists have identified the primary target of the experimental cancer drug CX-5164, revealing a possible risk for late effects of treatment.
Fat-secreted molecule lowers response to common cancer treatment
10. November 2021
Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study.
Cellular aging: A basic paradox elucidated
10. November 2021
Cancer researchers show for the first time that cellular senescence, which occurs when aging cells stop dividing, is caused by irreversible damage to the genome rather than simply by telomere erosion.
An innovative imaging technique for dynamic optical nanothermometry
10. November 2021
A new imaging technique can measure temperature in 2D, without contact, and in just a snap.
Corona-News: Narkoseärzte sehen wegen Coronawelle Akutversorgung in Gefahr
9. November 2021
Weil es so viele Coronapatienten gibt, drohen andere wichtige Operationen auszufallen. Vor diesem Szenario warnen Anästhesisten. Und Dänemark schränkt das öffentliche Leben wieder ein. Der Überblick.
Immunotherapy-chemotherapy treatment coupled with in-depth genomic analyses leads to improved survival for patients with mesothelioma
9. November 2021
Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial.
High cell membrane tension constrains the spread of cancer
9. November 2021
The membranes of cancer cells are more pliant than the membranes of normal cells. A research collaboration has discovered that cancer invasion and migration can be supressed in mice by manipulating the stiffness of the cell membrane. Hopefully this will contribute towards the development of new treatments that target the physical characteristics of cancer cells.
New symptoms identified that could help doctors diagnose pancreatic cancer
9. November 2021
Researchers have identified a series of symptoms associated with pancreatic cancer, including two previously unrecognised symptoms — feeling thirsty and having dark urine.
Corona-Impfung: Stiko hält Booster »mittelfristig« für alle für sinnvoll
9. November 2021
Booster für alle – oder nur für Menschen ab 70 Jahren? Nach uneinheitlichen Empfehlungen vonseiten der Politik und der Stiko, hat sich das Expertengremium jetzt geäußert.
Arginine, an inexpensive oral drug, could enhance radiation therapy for cancer
8. November 2021
Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial.
Corona-News am Montag: Österreich meldet Impf-Andrang vor Start der 2G-Regel
8. November 2021
In Österreich startet die 2G-Pflicht – am Wochenende drängten sich neue Impfwillige vor den Zentren. Lehrerverband hält 2G-Regel für Lehrkräfte sinnvoll. Und: Geimpfte dürfen jetzt in die USA einreisen. Der Überblick.
Corona in Deutschland: Sieben-Tage-Inzidenz springt laut RKI auf über 200
8. November 2021
Die vierte Coronawelle hat Deutschland voll erfasst: Laut Robert Koch-Institut stieg die Sieben-Tage-Inzidenz noch einmal massiv. Die Krankenhäuser befürchten bald deutlich mehr Intensivpatienten.
Corona: Lehrerverband warnt vor Kontrollverlust über Virus an Schulen
8. November 2021
Die Infektionszahlen steigen, auch unter jungen Menschen: Der Chef des Lehrerverbands fürchtet, dass die Coronalage an den Schulen schon bald nicht mehr beherrschbar sein könnte.