How alike are the cancer cells from a single patient?

Using an experimental system involving new genetic technology, researchers analyzed the gene expression signatures of a representative sample of barcoded leukemia cells. After implanting some of the leukemia cells in mice, they discovered that distinct gene expression signatures correlated with the various organs where the cancer cells ended up. They were also able to identify previously unknown genes that are involved in disease progression and chemotherapy resistance, which may offer new targets for treatment.

Quelle: Sciencedaily