New insights into the formation of ATP synthase-Researchers at University Hospital Bonn discover new Hsp70 function

Bonn, January 10, 2023 – Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the formation of ATP synthase, the turbine of the cells‘ power plants, the mitochondria. A so-called „molecular chaperone“, the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a „folding helper“ of proteins in mitochondria, but also promotes the assembly of ATP synthase. The new findings provide important findings for understanding how the ATP synthase is formed

Quelle: IDW Informationsdienst Wissenschaft