In its race to advance assisted reproduction and stem cell associated technologies to save the northern white rhinoceros from extinction, the BioRescue consortium announces a major breakthrough: the creation of primordial germ cell-like cells (PGCLSs) from induced pluripotent stem cells of the northern white rhino Nabire. This milestone was led by specialists from Osaka University, Japan, and has never been achieved in large mammals before. Now there is one last step to master for the production of artificial rhino gametes (eggs and sperm) from preserved tissue.