MEDIZIN.NEWZS.de – Quantum Related Diseases Research Group (QRDRG)

Viele fürchten sich vor Nebenwirkungen nach der Impfspritze, etwa einer Herzmuskelentzündungen. Forscher analysierten nun, ob diese tatsächlich häufiger nach einer Covid-19-Impfung vorkommt als nach anderen Impfungen.

Wie viel „Normalität“ ist jetzt möglich? Keine, glaubt man den Gelehrten. Über den schwierigen Übergang von der akuten Phase in ein neues „Leben mit dem Virus“.

A research group has analyzed how certain immune cells known as innate lymphoid cells (ILCs) develop into mature cells that play a part in inflammatory bowel disease (IBD). The findings could pave the way for more effective treatments against IBD, a disease that causes considerable suffering and that is linked to an increased risk of colorectal cancer.

Researchers undertook a systematic analysis of the molecular building blocks used to engineer therapeutic cells. Their work resulted in a comprehensive rule book for the design of therapeutic cells with improved specificity and safety, and for the eventual customization of cell-based therapies.

A study examined the differences in intratumoral immune responses between male and female cancers of non-reproductive origin.

Die Coronazahlen in Deutschland gehen weiter zurück: Zuletzt wurden dem Robert Koch-Institut 156.864 Neuinfektionen binnen 24 Stunden gemeldet. Die Einrichtung ruft weiter zu Impfungen und Maskentragen auf.

Wissenschaftler haben Hinweise darauf gefunden, dass Geimpfte auch bei Omikron nicht nur sich selbst vor den Folgen einer Ansteckung schützen. Anders als bei Delta braucht es dafür allerdings drei Impfungen.

Melanoma is a somewhat unusual cancer — one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs. Fortunately, when caught early, melanoma can often be cured by simple surgery, and there are now better treatments for advanced cases, including immunotherapies that prime a patient’s immune system to fight off the cancer. However, much remains unknown about melanoma, including the details of how it develops in the earliest stages, and how to best identify and treat the most dangerous early cases. Spatial maps of melanoma reveal how individual cells interact as cancer progresses.

Researchers want to improve their understanding of the immune environment in ovarian cancer in hopes of making immunotherapy an option for these patients. Researchers now report on key characteristics of immune cells in ovarian cancer and identify cell types important for mediating an immune response.

Using retrospective clinical data and in-depth lab studies, researchers have discovered that vitamin E can enhance immunotherapy responses by stimulating dendritic cells in the tumor.

Researchers have found a way to supercharge immune cells that could enable them to clear disease and infections faster

In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, researchers describe the mechanisms that modify the structure of T lymphocytes and hinder their migration towards the tumors to be destroyed. This discovery provides new perspectives on the migration of immune cells, a key process in antitumor immune defense.

In Deutschland wurden binnen 24 Stunden 165.368 Coronaneuinfektionen registriert – rund 36.000 Fälle weniger als vor einer Woche. Außerdem meldet das Robert Koch-Institut 310 weitere Todesfälle.

Researchers have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to new research. The findings open a new lead for understanding how tumors metastasize, or spread to other tissues, and hints at novel ways to block the spread of cancer by targeting the process.

Scientists have created a new roadmap that traces each step in the development of blood stem cells in the human embryo, providing scientists with a blueprint for producing fully functional blood stem cells in the lab. The research could help expand treatment options for blood cancers like leukemia and inherited blood disorders such as sickle cell disease.

A new study suggests that people with cancer and non-O blood types, such as types A, B, and AB, face an increased risk of developing venous thromboembolism (VTE), or blood clots in the veins, three months after their initial diagnosis. Scientists have long strived to understand the risk factors for VTE, the leading cause of preventable hospital deaths in the United States. Existing assessments use factors like tumor or cancer type to detect those at high risk of VTE. Yet, many patients without these diagnoses still develop life-threatening blood clots but go unidentified.

In den USA wurde eine Studie mit schwer kranken Patienten gestoppt. Das geprüfte Mittel verhinderte Todesfälle in der Analyse so gut, dass Fachleute es der Allgemeinheit nicht weiter vorenthalten wollen.

In Deutschland wurden 176.303 Neuansteckungen mit dem Coronavirus registriert. Die Zahl der Todesfälle stieg um 361.

Viele fürchten sich vor Nebenwirkungen nach der Impfspritze, etwa einer Herzmuskelentzündungen. Forscher analysierten nun, ob diese tatsächlich häufiger nach einer Covid-19-Impfung vorkommt als nach anderen Impfungen.

Die Pandemie ist noch nicht zu Ende, die Bilanzen sind schon da: Über die Kritik an Schweden und die Vorstellungen des Ethikrats und des Währungsfonds zur Zukunft des Pandemiemanagements.

Halluzinogene Substanzen werden gerne als Partydrogen konsumiert – doch Studien haben nachgewiesen, dass sie auch gegen Depressionen helfen. Was Psilocybin genau im Gehirn depressiver Menschen bewirkt, haben nun Londoner Forscher untersucht.

Cellular biologists discover why some patients become resistant to standard treatments for nonsmall cell lung cancer.

Researchers have developed a new computational tool to select optimal combination therapies for patients with cancer based on the co-occurring alterations in a given tumor.