Salamanders are the only terrestrial vertebrates that possess the remarkable ability to regenerate limbs or tails. The vast majority of research on vertebrate regeneration is based on the axolotl and has provided great insights on regenerative mechanisms. But how does regeneration proceed in other salamanders with different ecologies and life strategies, and which features are shared or variable? A new study by scientists at the Museum für Naturkunde Berlin, recently published open-access in the journal Developmental Dynamics, could show that data from other salamander species with different life history patterns and habitats is essential for advancing regeneration research in vertebrates.