Researchers from the Paul-Ehrlich-Institut (PEI) and the Main-Kinzig Clinics investigated the antibody response against various SARS-CoV-2 virus variants over time following COVID-19 mRNA (Comirnaty) vaccinations. After double vaccination against COVID-19, antibody levels against the Omicron variant are low. Omicron is currently the dominant variant in Germany. mRNA booster vaccinations significantly increase antibody levels against Omicron. Vaccines reports on the results.