SLC25A51 regulates the transport of the coenzyme NAD into the mitochondria

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism. Scientists in Giulio Superti-Furga’s research group at the CeMM have now discovered that the previously uncharacterised protein SLC25A51 acts as a transporter into the mitochondria for the coenzyme NAD. The results of this study not only open up new possibilities to study the biological role of NAD but also potentially provide the basis for new therapeutic approaches. The work has now been published in the journal Nature Communications.

Quelle: IDW Informationsdienst Wissenschaft