HIV-1: The undercover agent

Antibodies are not the only protection against viruses: At a much earlier stage, infected cells detect components of a virus with the help of internal sensors and trigger an immune response. This is an element of what is known as innate immunity, and helps prevent viruses from spreading further. In a new study, scientists from the Berlin Institute of Health (BIH) and Charité – Universitätsmedizin Berlin have now shown that the AIDS virus HIV-1 employs a sophisticated propagation strategy that causes the infection to go largely unnoticed in infected cells – at least in T cells, which are part of the body’s immune system. The scientists have published their findings in the PNAS journal.

Quelle: IDW Informationsdienst Wissenschaft