It is common knowledge that we inherit half of our genes from each parent. For the function of most genes, it doesn’t matter which parent a gene comes from. But this is not true for all genes: about 150 genes are subject to „genomic imprinting“, which means that, depending on the gene, they are active either only if inherited from the mother, or only if inherited from the father. Most of these „imprinted“ genes are important for our development. Simon Hippenmeyer, Professor at IST Austria, and his research group, including Susanne Laukoter and Florian Pauler, have now shown that brain cells react very differently to genomic imprinting, depending on the cell type.