Cell of origin in childhood brain tumors affects susceptibility to therapy

Children that are diagnosed with the severe the brain tumor malignant glioma often have a very poor prognosis. Knowledge about how pediatric malignant glioma arises and develops is still limited. New findings show that in mice glioma development and glioma cell properties are affected by both age and the cell type from which the tumor has arisen. The tumor cell of origin was also important for the susceptibility of the tumor cells towards cancer drugs. (Mehr in: Cancer News — ScienceDaily)