Mitochondria control stem cell fate

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich (TUM) addressed this question by generating a new model system. Functioning mitochondria play a decisive role in cellular homeostasis, but what happens when an important player of the anti-stress program in mitochondria is switched off? On the one hand, this leads to the loss of stem cells, but on the other, it sets healing processes in motion. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)