Evolution in Fast-Forward: How Thale Cress Adapts – or Goes Extinct

In an unprecedented field experiment, an international research team led by Goethe University Frankfurt, the University of California, Berkeley, and CNRS Montpellier investigated the evolutionary adaptation of thale cress (Arabidopsis thaliana) to a wide range of climates, from the Alps to the Negev Desert. At 30 locations worldwide, team members sowed the plants, monitored their development, and analyzed genetic changes. The result: many Arabidopsis populations rapidly adapted to local climates – some, however, went extinct. The findings demonstrate how genetic diversity ensures population survival. Quelle: IDW Informationsdienst Wissenschaft Hier jetzt das aktuell Außergewöhnliche auswählen …

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Europe’s Late Neanderthals descended from a single population

New study from the Senckenberg Nature Research Society and the University of Tübingen illustrates huge upheavals in Neanderthals’ genetic history Quelle: IDW Informationsdienst Wissenschaft Hier jetzt das aktuell Außergewöhnliche auswählen …

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Stomach Cancer: New Drug 60 Times More Effective Against Key Bacteria

• 60-fold greater efficacy than standard medication • Results achieved in laboratory and animal studies • 43 percent of the global population infected with H. pylori A significant step toward the potential prevention of stomach cancer: Researchers at the Technical University of Munich (TUM) have increased the effectiveness of a standard antibiotic by a factor of 60 through targeted chemical modifications. In laboratory and animal studies, the new drug candidate successfully combats the bacterium Helicobacter pylori, which is closely associated with the development of stomach cancer. The study findings were published in the journal Nature Microbiology. Quelle: IDW Informationsdienst Wissenschaft

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Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

Daniel Smeets, Yolanda Markaki, Volker J Schmid, Felix Kraus, Anna Tattermusch, Andrea Cerase, Michael Sterr, Susanne Fiedler, Justin Demmerle, Jens Popken, Heinrich Leonhardt, Neil Brockdorff, Thomas Cremer1, Lothar Schermelleh and Marion Cremer Abstract Background A Xist RNA decorated Barr body is the structural hallmark of the compacted inactive X territory in female mammals. Using super-resolution three-dimensional structured illumination microscopy (3D-SIM) and quantitative image analysis, we compared its ultrastructure with active chromosome territories (CTs) in human and mouse somatic cells, and explored the spatio-temporal process of Barr body formation at onset of inactivation in early differentiating mouse embryonic stem cells (ESCs)….

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