Schlagwort: Krebs
Half of all women experience false positive mammograms after 10 years of annual screening
26. März 2022
Half of all women experience a false positive mammogram after 10 years of annual breast cancer screening with 3D mammography, a UC Davis-led study estimates. This risk was lower for women who had mammograms every other year. 3D screening showed slightly lower false positive results than standard mammography.
Spinal fluid sampling used to track treatment response in pediatric glioma
26. März 2022
Treatment for glioma has long relied on MRI imaging to track tumor markers and treatment response. But new findings suggest a new method could provide additional data about tumor markers before changes appear on an MRI, indicating possible strategies to help clinicians address this aggressive form of cancer.
Novel method to identify and treat aggressive early-stage lung cancers
26. März 2022
Researchers have developed a novel method to identify aggressive early-stage lung cancers and target drugs known as aurora kinase inhibitors to tumors that are especially likely to respond to them. The findings could lead to great advances in treatment for lung adenocarcinoma, the most common type of lung cancer.
Study suggests association between consuming artificial sweeteners and increased cancer risk
25. März 2022
Artificial sweeteners reduce added sugar content and corresponding calories while maintaining sweetness. A new study suggests that some artificial sweeteners are associated with increased cancer risk.
Tuberculosis induces premature cellular aging
25. März 2022
Researchers found that the cells of humans and animals who have recovered from tuberculosis had prematurely aged up to 12 to 14 years. It’s possible that this premature cellular aging is one reason why survivors of tuberculosis have a high risk of mortality.
In animal study, implant churns out CAR-T cells to combat cancer
25. März 2022
Researchers have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors. In a proof-of-concept study involving lymphoma in mice, the researchers found that treatment with the implants was faster and more effective than conventional CAR-T cell cancer treatment.
Novel therapeutic strategy shows promise against pancreatic cancer
24. März 2022
Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.
FDA approved new immunotherapy regimen for patients with melanoma
24. März 2022
The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.
Getting fuel to an invading cell’s front line
23. März 2022
Invading armies need a steady supply of fuel and armaments. That’s just as true when the invaders are cells, such as when tumor cells break away and spread to other parts of the body in a process called metastasis — the most deadly part of cancer. Now, a study in C. elegans worms provides new insight into how invading cells deploy fuel to the front lines of invasion to power their break-through machinery.
Could diet modification make chemotherapy drugs more effective for patients with pancreatic cancer?
23. März 2022
The findings of a new study suggest that a ketogenic diet — which is low in carbohydrates and protein, but high in fat — helps to kill pancreatic cancer cells when combined with a triple-drug therapy. In laboratory experiments, the ketogenic diet decreased glucose (sugar) levels in the tumor, suggesting the diet helped starve the cancer. In addition, this diet elevated ketone bodies produced by the liver, which put additional stress on the cancer cells.
Chronologically young, biologically old: DNA linked to cancer survivors premature aging
23. März 2022
Scientists have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors.
Nanoparticle-based COVID-19 vaccine could target future infectious diseases
23. März 2022
Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use. And with minor changes, researchers hope the same vaccine platform could target other infectious diseases.
Researchers use ultrasound to predict ovarian cancer
23. März 2022
The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study.
Computational approach enables spatial mapping of single-cell data within tissues
22. März 2022
A new computational approach successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.
MRI innovation makes cancerous tissue light up and easier to see
22. März 2022
A new form of magnetic resonance imaging (MRI) that makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.
Youngest brain tumor patients have significantly poorer outcomes than older pediatric patients
19. März 2022
A researcher has found, through extensive data analysis, that the youngest patients with brain tumors — those ages birth to 3 months — have about half the five-year survival rate as children ages 1 to 19.
Bone marrow cancer: Potential drug targets
18. März 2022
New research finds that patients with ASXL1-mutant chronic myelomonocytic leukemia — an uncommon type of cancer of the bone marrow — have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster. The ASXL1 genetic mutation also can transform the disease into the more aggressive acute myeloid leukemia.
Pioneering technique could unlock targeted treatments for cancer
18. März 2022
Researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.
Scientists discover why women are more resistant to nonalcoholic fatty liver disease than men
18. März 2022
Nonalcoholic fatty liver disease (NAFLD) is one of the leading causes of death worldwide. However, why premenopausal women are more resistant to NAFLD than men is currently unknown. Now, scientists demonstrate, through sex-balanced experiments on mice, that the female liver produces higher levels of a protein that has a protective effect against NAFLD. Their findings could lead to new therapeutic strategies for treating NAFLD.
AI provides accurate breast density classification
18. März 2022
An artificial intelligence (AI) tool can accurately and consistently classify breast density on mammograms, according to a new study.
Researchers put a spotlight on aggressive cancer cells
18. März 2022
Metastases in cancer are often caused by a few abnormal cells. These behave more aggressively than the other cancer cells in a tumor. Researchers are now on a method to detect these cells.
Engineering an ‚invisible cloak‘ for bacteria to deliver drugs to tumors
18. März 2022
Researchers have genetically engineered a microbial encapsulation system for therapeutic bacteria that can hide them from immune systems, enabling them to reach tumors more effectively and kill cancer cells in mice.
Exposure to phthalates — the ‚everywhere chemical‘ — may increase children’s cancer risk
17. März 2022
New research has linked phthalates, commonly called the ‚everywhere chemical,‘ to higher incidence of specific childhood cancers.
A possible new COVID-19 vaccine could be accessible for more of the world
17. März 2022
A new protein subunit vaccine may offer an inexpensive, easy-to-store, and effective alternative to RNA vaccines for COVID-19.
New insights into how tumors metabolically adapt to their environment may lead to better cancer therapies
17. März 2022
A research team has discovered novel metabolic mechanisms that contribute to how ovarian cancer escapes from immune attack, and how combination therapies can exploit these pathways to improve ovarian cancer treatment.