Researchers have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors. In a proof-of-concept study involving lymphoma in mice, the researchers found that treatment with the implants was faster and more effective than conventional CAR-T cell cancer treatment.

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

Invading armies need a steady supply of fuel and armaments. That’s just as true when the invaders are cells, such as when tumor cells break away and spread to other parts of the body in a process called metastasis — the most deadly part of cancer. Now, a study in C. elegans worms provides new insight into how invading cells deploy fuel to the front lines of invasion to power their break-through machinery.

The findings of a new study suggest that a ketogenic diet — which is low in carbohydrates and protein, but high in fat — helps to kill pancreatic cancer cells when combined with a triple-drug therapy. In laboratory experiments, the ketogenic diet decreased glucose (sugar) levels in the tumor, suggesting the diet helped starve the cancer. In addition, this diet elevated ketone bodies produced by the liver, which put additional stress on the cancer cells.

Scientists have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors.

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use. And with minor changes, researchers hope the same vaccine platform could target other infectious diseases.

The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study.

A new computational approach successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.

A new form of magnetic resonance imaging (MRI) that makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.

A researcher has found, through extensive data analysis, that the youngest patients with brain tumors — those ages birth to 3 months — have about half the five-year survival rate as children ages 1 to 19.

New research finds that patients with ASXL1-mutant chronic myelomonocytic leukemia — an uncommon type of cancer of the bone marrow — have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster. The ASXL1 genetic mutation also can transform the disease into the more aggressive acute myeloid leukemia.

Researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.

Nonalcoholic fatty liver disease (NAFLD) is one of the leading causes of death worldwide. However, why premenopausal women are more resistant to NAFLD than men is currently unknown. Now, scientists demonstrate, through sex-balanced experiments on mice, that the female liver produces higher levels of a protein that has a protective effect against NAFLD. Their findings could lead to new therapeutic strategies for treating NAFLD.

An artificial intelligence (AI) tool can accurately and consistently classify breast density on mammograms, according to a new study.

Metastases in cancer are often caused by a few abnormal cells. These behave more aggressively than the other cancer cells in a tumor. Researchers are now on a method to detect these cells.

Researchers have genetically engineered a microbial encapsulation system for therapeutic bacteria that can hide them from immune systems, enabling them to reach tumors more effectively and kill cancer cells in mice.

New research has linked phthalates, commonly called the ‚everywhere chemical,‘ to higher incidence of specific childhood cancers.

A new protein subunit vaccine may offer an inexpensive, easy-to-store, and effective alternative to RNA vaccines for COVID-19.

A research team has discovered novel metabolic mechanisms that contribute to how ovarian cancer escapes from immune attack, and how combination therapies can exploit these pathways to improve ovarian cancer treatment.

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a new study.

Scientists have developed a genetic screening platform to identify genes that can enhance immune cells to make them more persistent and increase their ability to eradicate tumor cells.

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study suggests.

Treating cancer and other diseases with laser light is not currently considered routine, but new approaches using nanoparticles show some promise in improving existing techniques. Researchers review the status of the field and by combining photothermal therapy or photodynamic therapy with nanomaterials, they have been able to apply these types of phototherapies while also delivering drugs to sites in the body that are otherwise inaccessible. It is also possible to combine PTT and PDT into a single treatment, creating an even more powerful treatment method.

A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal models.