MEDIZIN.NEWZS.de – Quantum Related Diseases Research Group (QRDRG)

The gel, tested in mice, releases drugs and special antibodies that simultaneously deplete immune-blocking cells called macrophages from the surgical site and activate T cells so they can attack cancer.

Die Corona-Pandemie hat zu Beginn global die Laune der Menschen gedrückt – und zwar so sehr, wie gleich mehrere Montage, berichten Forscher.

Die Corona-Pandemie hat zu Beginn global die Laune der Menschen gedrückt – und zwar so sehr, wie gleich mehrere Montage, berichten Forscher.

Schweden setzte am Anfang der Pandemie statt auf Vorschriften auf Eigenverantwortung. Eine hohe Zahl von Todesopfern war die Folge. Schwedische Forscher üben nun massive Kritik.

Many cancers exhibit high levels of the reverse transcriptase enzyme. Single-agent lamivudine, a reverse transcriptase inhibitor, stopped disease progression in over 25% of patients with fourth-line refractory metastatic colorectal cancer. These results provide evidence for the evaluation of reverse transcriptase inhibitors as a new class of anti-cancer drugs.

Many cancers exhibit high levels of the reverse transcriptase enzyme. Single-agent lamivudine, a reverse transcriptase inhibitor, stopped disease progression in over 25% of patients with fourth-line refractory metastatic colorectal cancer. These results provide evidence for the evaluation of reverse transcriptase inhibitors as a new class of anti-cancer drugs.

Although clinical labs have known for almost a century that a oddly shaped nucleus resembling pince-nez glasses in blood cells could indicate leukemia, the cause of this anomaly remained unknown. Scientists have now discovered that loss of nuclear Lamin B1 induces defects in the nuclear morphology and in human hematopoietic [blood-forming] stem cells associated with malignancy. The scientists went on to detail that lamin B1 deficiency alters genome organization. This in turn causes expansion of blood-forming stem cells, a bias towards their becoming myeloids, genome instability due to defective DNA damage repair and other problems that set the stage for cancer.

Although clinical labs have known for almost a century that a oddly shaped nucleus resembling pince-nez glasses in blood cells could indicate leukemia, the cause of this anomaly remained unknown. Scientists have now discovered that loss of nuclear Lamin B1 induces defects in the nuclear morphology and in human hematopoietic [blood-forming] stem cells associated with malignancy. The scientists went on to detail that lamin B1 deficiency alters genome organization. This in turn causes expansion of blood-forming stem cells, a bias towards their becoming myeloids, genome instability due to defective DNA damage repair and other problems that set the stage for cancer.

Researchers have revealed how an ‚accordion effect‘ is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing. The finding expands our understanding of how we switch genes on and off to make the different cell types in our bodies, as we develop in the womb.

Researchers have revealed how an ‚accordion effect‘ is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing. The finding expands our understanding of how we switch genes on and off to make the different cell types in our bodies, as we develop in the womb.

Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer.

Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer.

A single nanoparticle does two jobs: enhancing the effectiveness of chemotherapy and reinvigorating the immune system.

In Großbritannien haben Fachleute eine neue Omikron-Untervariante ausgemacht. Wird sie BA.2 verdrängen? Führt sie zu schwereren Verläufen? Noch ist das unklar. Doch die Zahl der Fälle nimmt zu.

Das Robert Koch-Institut hat binnen 24 Stunden 340 neue Todesfälle im Zusammenhang mit dem Coronavirus registriert. Außerdem wurden 214.985 Neuinfektionen gemeldet.

»Laissez-faire« und »Ignoranz« – in einem neuen Bericht wird deutliche Kritik an Schwedens Pandemiepolitik laut. Der Tod vieler Menschen sei willentlich in Kauf genommen worden.

In Deutschland haben sich laut Robert Koch-Institut weitere 180.397 Menschen mit dem Coronavirus infiziert. Außerdem wurden 316 Todesfälle gemeldet.

Fast die gesamte Menschheit leidet laut Weltgesundheitsorganisation unter zu hohen Schadstoffwerten. Schuld an der schlechten Luftqualität sind nicht nur Autos.

China hat am Sonntag mehr als 13.000 neue Coronafälle registriert. Unterdessen hält die Regierung an der Null-Covid-Strategie fest – in den sozialen Netzwerken Chinas hagelt es dafür Kritik.

Auch die absolute Zahl der Neuinfektionen ist laut Robert Koch-Institut im Vergleich zum Vortag gesunken. In der Nacht zum Sonntag gingen vielerorts zahlreiche Coronaschutzmaßnahmen zu Ende.

Diesen Winter erkrankten bisher nur wenige an der Grippe, doch das könnte sich mit dem Wegfall der Pandemie-Maßnahmen ändern. Wer sich gleichzeitig mit Sars-CoV-2 und dem Influenzavirus ansteckt, dem könnte ein besonders schwerer Krankheitsverlauf drohen.

In allen Bundesländern außer Hamburg und Mecklenburg-Vorpommern laufen Maskenpflicht und Zutrittsbeschränkungen aus. Doch Vertreter von Ärzten und Kliniken warnen vor verfrühten Lockerungen.

Zinc’s immune-boosting properties are well-established, but scientists haven’t known exactly how it works. Scientists now reveal two ways the mineral supports immunity and suggest how it could be used to improve health. Using mice, the team discovered that zinc is needed for the development of disease-fighting immune cells called T cells and prompts regeneration of the thymus, the immune organ that produces T cells.

A new study uses next-generation gene sequencing to get a clearer read on the community of viruses present in vaginal microbiome samples and its implication for the development of cervical cancer.

Wer an Covid-19 erkrankt, hat ein höheres Risiko, im Jahr danach Diabetes zu entwickeln, zeigt eine Studie mit rund 180.000 Probanden. Die Fachleute warnen vor einem »Vermächtnis chronischer Krankheiten«.