Cells organize their molecules in distinct functional areas. While textbooks usually refer to membrane-bound organelles such as mitochondria and cell nuclei, recent studies have also revealed organelles without membranes. These include stress granules and proteasome storage granules (PSGs). In the past, these membraneless organelles were only visible as “droplets” using a fluorescence microscope. Now, researchers from the Max Planck Institute of Biochemistry in Martinsried, University Medical Center Göttingen, and University of Toronto have defined the detailed structures of molecules in PSGs for the first time, using cryoelectron tomography. The results were published in the journal Cell.