Long shifts, irregular working hours, high time pressure, and social isolation: the work of freight train drivers is both physically and mentally demanding. A better understanding of the specific work-related stresses faced by freight train drivers can help make the profession more sustainable and attractive in the long term. To this end, a research team at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) studied 532 train drivers in Germany, examining how various psychosocial factors and their interactions influence well-being, performance, and safety.