In the journal “Science Translational Medicine”, scientists from DZNE and LMU Hospital report on new insights into the mechanisms of “Niemann-Pick type C” (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood. Their findings, based on studies in mice, cell cultures and patients, emphasize that neuroinflammation, which is mediated by the brain’s immune system, plays a crucial role in NPC