TLR8 influences the production of disease-related cytokines

Systemic sclerosis is an autoimmune disease that primarily causes inflammation of the skin, as well as internal organs such as the lungs and heart. It is considered a rare disease, and little is yet known about its development and progression. In cooperation with the Departments of Rheumatology and Immunology, as well as Dermatology at the Hannover Medical School, a team led by junior research group leader Theresa Graalmann at TWINCORE, Centre for Experimental and Clinical Infection Research, has investigated the role of a specific group of immune cells in people with systemic sclerosis.