At the turn of the millennium, grey wolves returned to Germany after 150 years and subsequently established territories in many parts of the country. But coexistence harbours challenges – for both humans and animals. Since 2006, almost all grey wolves found dead in Germany have been examined at the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) in order to assess their health status and determine the cause(s) of death. Recently, the 1000th wolf lay on the dissecting table at the Leibniz-IZW. The female animal died as a result of a road accident – by far the most common unnatural cause of death for grey wolves in Germany.