Acetaminophen poisoning (APAP) is the second most common cause of liver transplantation worldwide. However, not all the correlations that lead to liver damage from APAP are yet known. With the help of functional imaging, the Leibniz Research Centre for Working Environments and Human Factors in Dortmund (IfADo) is therefore investigating in a new research project, on the one hand, how temporary bile stasis after APAP poisoning contributes to liver damage. On the other hand, research is being conducted to find out whether this liver damage can be reduced by medication. The project is funded by the German Research Foundation (DFG) and will run for three years.