The short lifespan of the turquoise killifish (N. furzeri) makes it an important model organism for aging research. However, its husbandry and breeding present research institutions with challenges: The fish have a short lifespan and must be continuously bred, while at the same time their genetic diversity must be preserved. Researchers at the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) have therefore developed the Dynamic Population Breeding (DPB) method. This new breeding concept improves the survival rate of offspring, reduces differences between breeding cohorts, and thus creates an important foundation for reproducible and sustainable research on biological aging.