Schlagwort: metastasis
Evidence in mice that bacteria in tumors help cancer cells metastasize
Cause of metastasis in prostate cancer discovered
Cause of metastasis in prostate cancer discovered
Getting fuel to an invading cell’s front line
Researchers reduce breast cancer metastasis in animal models by modifying tumor electrical properties
Reducing copper in the body alters cancer metabolism to reduce risk of aggressive breast cancer
Small molecule may prevent metastasis in colorectal cancer
Different types of cancers are likely to spread to specific areas of the brain
Experimental model of ovarian cancer shows effect of healthy cell arrangement in metastasis
Discovery within human cell cycle process to bring new understanding of cellular diseases
Drug doubles down on bone cancer, metastasis
Pinpointing how cancer cells turn aggressive
Causal mechanism of link between cancer and obesity
First detailed look at crucial enzyme advances cancer research
Embryonic tissue undergoes phase transition
New organelle involved in cancer metastasis
Membrane around tumors may be key to preventing metastasis
Genomic test helps estimate risk of prostate cancer metastasis, death
Cancer models created by mechanical engineers offer new insight into tumor growth
Changing the perspective on the ‚Cinderella of the cytoskeleton‘
Mitochondria and the evolutionary roots of cancer
Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to inhibitory signals, evasion of programmed cell death and limitless replicative potential with a potential for the invasion of other organs. Cancer disease is widespread among metazoans. Some properties of cancer cells such as uncontrolled cell proliferation, lack of apoptosis, hypoxia, fermentative metabolism and free cell motility, i.e. metastasis, resemble a prokaryotic lifestyle, which leads to the assumption of a reversal like evolution from eucariotic back to proteobacterial state. This phenotype matches the phenotype of the last universal common ancestor (LUCA) that resulted from the endosymbiosis between archaebacteria and α-proteobacteria, which later became the mitochondria.