Schlagwort: metastasis
Understanding metastasis mechanisms
Biology: Publication in Nature Communications Metastases, i.e. the secondary growths of cancer cells, are a key problem in many types of cancer. As descendants of the primary tumour, they can grow in other organs distant from the primary site and are often difficult to identify. A research team from the Institute of Genetics at Heinrich Heine University Düsseldorf (HHU) has now identified molecular mechanisms, which can enable cancer cells to colonise other tissue. The team led by Dr Tobias Reiff has now published its findings in the scientific journal Nature Communications. Quelle: IDW Informationsdienst Wissenschaft Hier jetzt das aktuell Außergewöhnliche…
Mitochondria and the evolutionary roots of cancer
Cancer is a group of almost 200 diseases that involve variety of changes in cell structure, morphology, and physiology. Cancer phenotype is underlying several alterations in cellular dynamics with three most critical features, which includes self-sufficiency in growth signals and insensitivity to inhibitory signals, evasion of programmed cell death and limitless replicative potential with a potential for the invasion of other organs. Cancer disease is widespread among metazoans. Some properties of cancer cells such as uncontrolled cell proliferation, lack of apoptosis, hypoxia, fermentative metabolism and free cell motility, i.e. metastasis, resemble a prokaryotic lifestyle, which leads to the assumption of…