Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this complicated network requires a precise look into how these nerve cells are arranged and connected. “LICONN”, a new microscopy method developed by scientists at the Institute of Science and Technology Austria (ISTA) and Google Research, now helps piece together this puzzle. The method, which makes use of off-the-shelf light microscopes, hydrogel and deep learning, was published in Nature.