Study: Significant antiviral activity of the agent bulevirtide for the treatment of chronic hepatitis D virus infection

Between 10 and 20 million people worldwide are infected with hepatitis D virus (HDV). HDV infection is always associated with hepatitis B virus infection. So far there has been no satisfactory therapeutic option for this most severe form of chronic viral hepatitis. In a multicenter Phase II clinical trial, an international research team was now able to show that the 24-week application of the drug candidate bulevirtide, developed by DZIF virologist Prof. Stephan Urban, significantly reduced hepatitis D viral load in blood serum and liver. Treatment with the novel entry inhibitor therefore represents a promising strategy for patients with chronic HDV infection.

Quelle: IDW Informationsdienst Wissenschaft