Case solved: the biosynthesis of strychnine elucidated

Researchers from Jena report in the journal Nature how the poison nut tree forms strychnine. A research team at the Max Planck Institute for Chemical Ecology in Jena disclosed the complete biosynthetic pathway for the formation of strychnine in the plant species Strychnos nux-vomica (poison nut). The researchers identified all genes involved in the biosynthesis of strychnine and other metabolites and expressed them in the model plant Nicotiana benthamiana. This enabled them to show that these extremely complex and pharmacologically important molecules can be synthesized using „metabolic engineering“ methods

Quelle: IDW Informationsdienst Wissenschaft