EpiBlok is developing a gene therapy for epilepsy

During an epileptic seizure, groups of neurons suddenly fire all at once, leading to involuntary movements and sensations. Possibilities for helping those who suffer from epilepsy are limited. EpiBlok Therapeutics GmbH was recently founded by scientists from Charité and the Medical University of Innsbruck. The company is developing a type of gene therapy in which an adeno-associated virus transports the gene for the neuropeptide dynorphin into selected neurons of the affected brain region. The goal is the long-term suppression of seizures, by having the neurons produce a reserve supply of dynorphin that can be released when needed.

Quelle: IDW Informationsdienst Wissenschaft