Immunosuppressed patients often cannot build up good protection after a vaccination because the necessary cells of the immune system function less well or are not present at all. This has been studied especially in the drug therapy of rheumatoid arthritis. Scientists from TWINCORE and the Hannover Medical School have now published in the journal Annals of the Rheumatic Diseases the circumstances under which this group of people can nevertheless be successfully vaccinated. Based on their data, they recommend a promising strategy for the COVID-19 vaccination of rheumatism patients who are treated with the drug Rituximab.
Communication between immune cells determines response to vaccination