New tool helps to ‘spot the difference’ in genome organisation

The way DNA is organized in the cell nucleus is very important for the normal development and function of the cell. A mutation that affects the packaging of the genetic material in the cell nucleus can lead to developmental disorders or diseases such as cancer. A team of scientists from the Max Planck Institute in Münster, the MRC London Institute of Medical Sciences in London and the Center for Genomic Regulation in Barcelona has developed a method for automated analysis of the 3D genome organization in different cell populations (Nature Genetics, October 19, 2020). This enables scientists to track down causes of diseases more quickly.

Quelle: IDW Informationsdienst Wissenschaft