Puzzle solved after 16 years

A research group from Würzburg has now been able to clarify the long-standing question of how the protein complex CDK-activating kinase (CAK), which controls the central processes of cell division and transcription, is activated. The group analyzed the active form of the protein/CAK complex and was able to decipher its function on a molecular level. These new findings provide the basis for further research on cancer drugs and were published in the renowned scientific journal PNAS.

Quelle: IDW Informationsdienst Wissenschaft