Duplications and inversions of DNA segments lead to the masculinization of female moles

Joint press release of the Max Planck Institute for Molecular Genetics, Charité – Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine

Female moles not only have ovarian, but also testicular tissue that produces male sex hormones – which lets them diverge from the categorization into two sexes. A team led by Berlin researchers Stefan Mundlos and Darío Lupiáñez describes in „Science“ which genetic modifications contribute to this singular development.