Real-time observation of signal transmission in proteins provides new insights for drug research

Proteins transduce information and signals within the human body by changes in their structures. For example, hormones binding to their target proteins cause a structural change which in turn opens new binding sites for other proteins elsewhere on the surface of the protein. Researchers refer to this coupling of different, distant binding sites as allostery. An interruption of this coupling leads to signals not being passed on.

Quelle: IDW Informationsdienst Wissenschaft