Biological markers that could guide treatment for prostate cancer

Genetic alterations in low-risk prostate cancer diagnosed by needle biopsy can identify men that harbor higher-risk cancer in their prostate glands, researchers have discovered. The research found for the first time that genetic alterations associated with intermediate- and high-risk prostate cancer also may be present in some cases of low-risk prostate cancers. (Mehr in: Cancer News — ScienceDaily)

Prostate cancer: New computer model enables researchers to predict course of disease

How does a normal cell turn into a deadly cancer? Seeking an answer to this Question researchers examined the tumor genomes of nearly 300 prostate cancer patients. Their findings describe the ways in which changes in the prostate cells‘ genetic information pave the way for cancer development. Using a newly developed computer model, it is now possible to predict the course of the disease in individual patients. (Mehr in: Cancer News — ScienceDaily)

Faster, cheaper test can help predict risk of metastasis in prostate cancer patients

A report describes a new assay to assess copy number alterations that is cheaper, faster, reproducible, and requires less tissue than other diagnostic techniques and has the potential to significantly enhance prostate cancer evaluation. (Mehr in: Cancer News — ScienceDaily)

Inflammatory bowel disease linked to prostate cancer

Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer. This is the first report to show these men have higher than average PSA values and a significantly higher risk of potentially dangerous prostate cancer. They need to be screened more carefully for prostate cancer. About 1 million men have inflammatory bowel disease in the U.S., a common chronic condition that includes Crohn’s disease and ulcerative colitis. (Mehr in: Cancer News — ScienceDaily)

Revolutionary technology pinpoints biopsies to detect prostate cancer

Medical software that overlays tumor information from MRI scans onto ultrasound images can help guide surgeons conducting biopsies and improve prostate cancer detection. (Mehr in: Cancer News — ScienceDaily)

Reliance on ‚YouTube medicine‘ may be dangerous for those concerned about prostate cancer

The most popular YouTube videos on prostate cancer often offer misleading or biased medical information that poses potential health risks to patients, an analysis of the social media platform shows. The study of the 150 most-viewed YouTube videos on the disease found that 77 percent had factual errors or biased content in either the video or its comments section. (Mehr in: Cancer News — ScienceDaily)

Study identifies a genetic driver of deadly prostate cancer

A new study has identified a novel molecular driver of lethal prostate cancer, along with a molecule that could be used to attack it. The findings were made in laboratory mice. If confirmed in humans, they could lead to more effective ways to control certain aggressive types of prostate cancer. (Mehr in: Cancer News — ScienceDaily)

Scientists neutralize reactive nitrogen molecules to enhance cancer immunotherapy

Researchers studying tumors in prostate cancer models found that nitration of an amino acid can inhibit T-cell activation, thwarting the T-cell’s ability to kill cancer cells. (Mehr in: Cancer News — ScienceDaily)

New genetic compound marker could help early diagnosis of aggressive prostate cancer

A research team has discovered a link between the interplay of certain simultaneously occurring genetic changes in the HOXB13 and CIP2A genes, aggressiveness of prostate cancer, high risk of developing the disease, and poorer survival rates of patients. Prostate cancer is a major challenge in health care with over one million new cases and 300,000 deaths from it each year worldwide. (Mehr in: Cancer News — ScienceDaily)

Experts advise against routine testing for prostate cancer

Routine testing for prostate cancer is not recommended for most men because the benefit is small and uncertain and there are clear harms, say experts in a new article. (Mehr in: Cancer News — ScienceDaily)

Hormone therapy can make prostate cancer worse, study finds

Scientists have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur. (Mehr in: Cancer News — ScienceDaily)

New genetic marker could help diagnose aggressive prostate cancer

A new link has been found between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients. (Mehr in: Cancer News — ScienceDaily)

Nuclear gatekeeper could block undruggable prostate cancer targets

Blocking nuclear gateways that traffic cancer-promoting molecules to nucleus, could offer a new way to target aggressive cancer. (Mehr in: Cancer News — ScienceDaily)

Common skin cancer can signal increased risk of other cancers

People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study. (Mehr in: Cancer News — ScienceDaily)

Low-protein diet during pregnancy increases prostate cancer risk in offspring, rat study shows

Experiments with rats show that intrauterine protein restriction induces sex hormone imbalance, which appears to favor development of cancer in old age. The rate of prostate tumor development reached 50 percent among the old rats submitted to low-protein diet during pregnancy and lactation alike. (Mehr in: Cancer News — ScienceDaily)

Blood test can predict optimal treatment for advanced prostate cancer, study finds

Scientists have demonstrated that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival. (Mehr in: Cancer News — ScienceDaily)

The cause of prostate cancer progression to incurable stage has likely been uncovered

Researchers have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. (Mehr in: Cancer News — ScienceDaily)

RNA molecules that regulate action of male hormone in prostate cancer identified

A study detected in tumoral tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tumors. By investigating the connection between the presence of these molecules and tumor aggressiveness, the research paves the way for new scientific approaches focusing on the transcription process of noncoding RNA. (Mehr in: Cancer News — ScienceDaily)

Early supper associated with lower risk of breast and prostate cancer

People who have their evening meal before 9 p.m. or wait at least two hours before going to sleep have lower risk of breast and prostate cancer. (Mehr in: Cancer News — ScienceDaily)

Deadly form of advanced prostate cancer is common, calls for distinct treatment

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers — about 17 percent — belong to a deadlier subtype of metastatic prostate cancer. (Mehr in: Cancer News — ScienceDaily)

Prostate cancer ultrasound treatment as effective as surgery or radiotherapy

Using high energy ultrasound beams to destroy prostate cancer tumours may be as effective as surgery or radiotherapy, but with fewer side effects. (Mehr in: Cancer News — ScienceDaily)

Obesity affects prostate cancer test results

New research shows that the results of the most widely used test for prostate cancer may be affected by obesity. (Mehr in: Cancer News — ScienceDaily)

New subtype of prostate cancer

Researchers have identified a new subtype of prostate cancer that occurs in about 7 percent of patients with advanced disease. This subset of tumors were responsive to immunotherapy treatment. (Mehr in: Cancer News — ScienceDaily)

Genetic markers for prostate cancer

Scientists found telltale genetic markers that can be used to predict those most at risk of prostate cancer, a disease common for older men. (Mehr in: Cancer News — ScienceDaily)

Inexpensive detector is like ‚Velcro®‘ for cancer cells

Researchers have developed a new type of sensor that acts like Velcro® for prostate cancer cells, sticking them to a modified frosted glass slide, like those used in science classes, so that they can be identified from blood samples. The low-cost method could help doctors better diagnose and monitor the disease. (Mehr in: Cancer News — ScienceDaily)