Quell: IDW Informationsdienst Wissenschaft

Quell: IDW Informationsdienst Wissenschaft

Quell: IDW Informationsdienst Wissenschaft

Quelle: Sciencedaily

Quell: IDW Informationsdienst Wissenschaft

Quell: IDW Informationsdienst Wissenschaft

Quelle: Sciencedaily

Quell: IDW Informationsdienst Wissenschaft

Quelle: Sciencedaily

Scientists have succeeded for the first time in directly reprogramming human blood cells into a previously unknown type of neural stem cell. These induced stem cells are similar to those that occur during the early embryonic development of the central nervous system. They can be modified and multiplied indefinitely in the culture dish and can represent an important basis for the development of regenerative therapies. (Mehr in: Cancer News — ScienceDaily)

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells. The results reveal a potential new treatment approach for an aggressive blood cancer with a poor prognosis. (Mehr in: Cancer News — ScienceDaily)

Botryllus schlosseri, a marine invertebrate that lives in underwater colonies resembling fuzzy pinheads clinging to rocks, has a blood-forming system with uncanny similarities to that of humans, according to scientists. (Mehr in: Cancer News — ScienceDaily)

Researchers are presenting preliminary results from a clinical study of an investigational cellular immunotherapy for Hodgkin lymphoma and non-Hodgkin lymphoma expressing the CD30 protein marker. (Mehr in: Cancer News — ScienceDaily)

Clinical trial results show a 91 percent response rate to the combination of venetoclax with azacitidine in older adults newly diagnosed with acute myeloid leukemia (AML). Of 33 patients given combination venetoclax and azacitidine, 20 experienced a complete response (aka complete remission) and eight experienced a complete response but with continued low blood counts. (Mehr in: Cancer News — ScienceDaily)

Bioengineers have developed a 3D bioprinting technique that works with natural materials and is easy to use, allowing researchers of varying levels of technical expertise to create lifelike tissues, such as blood vessels and a vascularized gut. The goal is to make human organ models that can be studied outside the body or used to test new drugs ex vivo. (Mehr in: Cancer News — ScienceDaily)

Researchers have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of the mutations in the DNA is relevant. Using the mutation patterns in the hematopoietic stem and progenitor cells (HSPCs) the team was able to trace the developmental lineage tree of the cells. (Mehr in: Cancer News — ScienceDaily)

In a new study, researchers describe a method for pinpointing tumor-specific factors in blood that can elicit a protective immune response in the body and may one day be harnessed to produce an effective vaccine against the disease. (Mehr in: Cancer News — ScienceDaily)

Researchers say they have added to evidence that measuring and monitoring tumor DNA that naturally circulates in the blood of melanoma patients can not only reliably help reveal the early stages of cancer growth and spread but also uncover new treatment options that tumor genetic analysis alone may not. (Mehr in: Cancer News — ScienceDaily)

Cancer scientists have combined ‚liquid biopsy,‘ epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages. (Mehr in: Cancer News — ScienceDaily)

A clot in a blood vessel can block the artery. This is what doctors call thrombosis. To prevent thrombosis, exercises for legs and feet help. Often, however, those affected lack motivation. The computer game “jumpBALL”, developed by Kaiserslautern researchers together with medical doctors, provides helpful support. What is special: It’s controlled by your feet. The researchers have developed it to be used with smartphones and tablets. The game can also help after a stroke or hip or knee surgery. At the Medica medical technology trade fair in Düsseldorf from 12 to 15 November, researchers will present the game at the research stand of Rhineland-Palatinate (hall 7a, stand B06). (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Researchers have identified blood-based biomarkers that may help identify those patients at greatest risk of developing autoimmune side effects from the treatment. (Mehr in: Cancer News — ScienceDaily)

In new research aimed at aiding cancer detection and treatment, scientists might have found the ideal surface texture for helping microscopic, medical helpers to survive in the bloodstream without being screened out by the body’s natural defense mechanisms. (Mehr in: Cancer News — ScienceDaily)

EARTO Award for Microsystem of the Fraunhofer IWS Dresden

(Dresden, 17.10.2018) Dresden Fraunhofer engineers have developed a so-called „multi-organ chip“. This microsystem from the Fraunhofer Institute for Material and Beam Technology IWS Dresden, which has now received an „EARTO Innovation Award“ in Brussels, simulates the blood circulation and the organs of animals or humans. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)

Data on the molecular makeup and drug sensitivity of hundreds of patient samples could accelerate progress against the aggressive blood cancer acute myeloid leukemia. (Mehr in: Cancer News — ScienceDaily)

Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. However, scientists know little about the early stages of the condition. Now, researchers have discovered that host responses during sepsis progression can vary in important ways based on pathogen type — which could lead to more effective treatments. (Mehr in: Cancer News — ScienceDaily)