Magnetic resonance imaging (MRI) is indispensable in medical diagnostics. However, MRI units are large and expensive to acquire and operate. With smaller and cost-efficient systems, MRI would be more flexible and more people could benefit from the technique. Such mini MRI units generate a much weaker signal that is difficult to analyze, though. Researchers at the Max Planck Institute (MPI) for Biophysical Chemistry and the Center for Biostructural Imaging of Neurodegeneration have now developed a method amplifying the signal so much that they could monitor a metabolic reaction in real time with a miniature MRI. This is an important contribution to making flexible small MRI devices usable.