Our body can repair damage to our DNA that can lead to the development of cancer by means of repair complexes. But how does the repair machinery recognize the damage? Scientists from the University of Würzburg and the University of Kent have now identified a complex that plays an important role in damage recognition in nucleotide excision repair. Due to its key position, the complex represents a starting point for research on cancer drugs. The results were published in the renowned journal Nucleic Acids Research.
New complex for damage detection in DNA identified