p53 mutations in 10,000 cancer patients shed new light on gene’s function

One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. Researchers have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene. Their findings shed light on how the gene becomes mutated and how those mutations can help predict clinical outlook.

Quelle: Sciencedaily