Aging and stress lead to an increased risk of disease and intensified inflammatory processes. We don’t know the underlying reason. What we do know, however, is that aging and stress have an impact on epigenetics, i.e., they influence whether certain genes are transcribed stronger, weaker or not at all. Epigenetic changes occur normally but they can be accelerated by aging and stress. The more stress, the quicker the “epigenetic aging”. Researchers at the Max Planck Institute of Psychiatry have tackled the question of whether the epigenetic effects caused by aging and stress can influence the function of molecules that are involved in inflammatory processes.