Unique jumps in the genome

Mobile elements or retrotransposons occupy more than half of the human genome – with a complex and multifaceted influence on our existence. On the one hand, they can fortuitously acquire important functions influencing the structure and regulation of our genes. On the other hand, uncontrolled multiple jumps can lead to genetic diseases and mistakes in gene regulation. Liliya Doronina and colleagues from the Medical Faculty of the University of Münster, investigated (i) how frequently do mobile elements independently insert into an identical genomic place in two organisms and (ii) how frequently are established mobile elements exactly excised from their genomic locus.

Quelle: IDW Informationsdienst Wissenschaft