Largest genetic study of osteoarthritis reveals possible new routes for treatment

Scientists have uncovered 52 new genetic changes linked to osteoarthritis, which doubles the number of genetic regions associated with the disabling condition. In the largest genetic study of osteoarthritis to date comprising about 480.000 participants, the researchers revealed new biological pathways linked to osteoarthritis, which could help identify starting points for new medicines. Researchers also highlighted opportunities for existing medicines to be evaluated in osteoarthritis. The study in ‘Nature Genetics’ was led by Prof. Dr. Eleftheria Zeggini who recently joined Helmholtz Zentrum München. Follow the link to see her explaining the paper in a nutshell: https://vimeo.com/312537973

Quell: IDW Informationsdienst Wissenschaft