Stem cells conduct cartilage regeneration but are not directly involved

Stem cell therapy has great potential for curing cartilage damage. However, it has remained unclear whether stem cells are responsible for regeneration or whether they trigger the process. Researchers at the Vetmeduni Vienna have been able to resolve this issue by tracking the effects in a new, natural model. After injection, stem cells orchestrate the healing effect of endogenous cells but are not responsible for cartilage regeneration. The breakthrough is published in JCI-Insight and was enabled by preventing the normal immune response to the molecule required to trace the injected cells. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)