Mapping DROSHA’s cleavage sites

Each cell of our body is the result of an orchestra of sophisticated mechanisms that control which genes are and are not expressed at any given time. Partly, this is possible thanks to the coordination of several types of RNA molecules, like microRNAs (miRNAs). Researchers have developed a new technique called fCLIP-seq that analyzes the miRNA fragments created by the RNA-cleaving protein DROSHA. It is expected that this study will open up new pathways to understand the role of DROSHA in such important biological phenomena. (Mehr in: Cancer News — ScienceDaily)