Gene Variant in Conjunction with High-Fat Diet Linked to Increased Blood Pressure

The endogenous enzyme ACE* plays a major role in blood pressure regulation. As a twin study led by the German Institute of Human Nutrition (DIfE), a partner of the German Center for Diabetes Research, has now shown for the first time, a high-fat diet causes the enzyme levels in the blood to rise within six weeks. Carriers of a specific ACE gene variant also responded with an increase in blood pressure. The identified variant could therefore potentially be used as a diet-dependent risk marker, according to the researchers. In addition to LDL cholesterol, ACE may be a further link between fat intake and the development of cardiovascular diseases. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)