To divide or not: A cellular feedback loop enables new cells to make a fateful decision

New research sheds light on a critical decision every newly born cell makes: whether to continue to proliferate or exit the cell-division cycle. In cancer, the equivalent of an ‚on‘ switch is stuck in that position. In healthy cells, the team has discovered, the opposing effects of proteins ORC1 and CDC6 in controlling the level of Cyclin E contributes to the stability of the genome. (Mehr in: Cancer News — ScienceDaily)