New mechanism activates the immune system against tumour cells

Only when cancer cells escape the surveillance by the immune system can a tumour grow. It is currently one challenge in cancer research to activate the body’s natural defences to eliminate tumour cells. Veronika Sexl, head of the Institute of Pharmacology and Toxicology at the University of Veterinary Medicine Vienna, has now discovered with her team a surprising new function for the signalling molecule STAT1 in immune cells. This previously unknown feature could pave the way to a new therapeutic approach to immunological cancer therapy. The study results were published in the journal ‘OncoImmunology’. (Mehr in: Pressemitteilungen – idw – Informationsdienst Wissenschaft)